Evolution of calcitonin gene-related peptide family from invertebrates to vertebrates Event as iCalendar

(Biological Science, Biological Sciences, Seminars)

26 February 2018

1 - 2pm

Venue: Mac 1

Location: 5 Symonds Street, Auckland Central

Host: SBS

Contact info: Debbie Hay

Contact email: dl.hay@auckland.ac.nz

Dr Toshio Sekiguchi from Noto Marine Laboratory (Division of Marine Environmental Studies, Institute of Nature and Environmental Technology, Kanazawa University, Japan) and his collaborators are investigating the evolution of neural and hormonal peptides from invertebrates to vertebrates.

In this talk, Dr Sekiguchi will focus on the calcitonin gene-related peptide (CGRP) family. CGRP family peptides comprise CGRP, calcitonin, adrenomedullin, amylin and CRSP.  Although CGRP family peptides have varied distribution and function in vertebrates, their genes are likely to be derived from a common ancestor. 

Dr Sekiguchi will indicate the molecular characteristics and pharmacological role of CGRP family peptides and their receptors in amphioxus and ascidian,  which are invertebrate species close to vertebrates, and provide a hypothesis on the evolutionary process of the CGRP family.

Contact: Debbie Hay, dl.hay@auckland.ac.nz   

Time/Place: Monday 26th February 1-2pm, Mac 1