From function to sequence with single-cell resolution Event as iCalendar

(Biological Sciences, Seminars)

16 April 2018

1 - 2pm

Venue: Mac 1, Biology Building

Location: 5 Symonds Street, Auckland Central

Host: SBS

Contact info: Mike Taylor

Contact email: mw.taylor@auckland.ac.nz

Speaker: Dr Tanja Woyke, Joint Genome Institute, USA

Most microbial single-cell sequencing projects rely on random cell isolation followed by rRNA-based selection of which cells to sequence. As technologies mature, targeted cell capture is becoming a tractable and highly attractive alternative.

Such capture provides unique selectivity for studying environmental microbes by zooming in on a biological process or phenotype of interest and separating these uncultivated organisms from their often complex community, prior to sequencing.

Dr Tanja Woyke will discuss examples of this function-driven single-cell genomics approach, highlighting their potential as a powerful addition to the genomics toolkit, providing a glimpse beyond ‘just’ the coding potential of the microbial world.