Force sensing and generation in biology | Towards the origins of motility Event as iCalendar

25 February 2019

1 - 2pm

Venue: Mac 1 Biology Building

Location: 5 Symonds St

Host: SBS

Contact info: Dr Kristal Cain

Contact email: k.cain@auckland.ac.nz

Dr Matt Baker
Dr Matt Baker

Speaker: Dr Matt Baker, School of Biotechnology and Biomolecular Sciences and EMBL Australia Node for Single Molecule Science, University of New South Wales, Australia


Dr Matt Baker is a biophysicist who examines generating and sensing forces in biology. On the force generation side he studies the bacterial flagellar motor that makes nearly all bacteria swim. Dr Baker’s career has focused on the mechanism for motor assembly and how interactions between simple subunits can dictate the overall assembly of complex architectures. The next question that interests him is how such complexity emerged. To address this, Dr Baker’s nascent group at the University of New South Wales uses directed evolution to examine the evolutionary landscape that constrains the adaptation of the motor.

On the sensing side, Dr Baker examines mechanosensitive channels in custom in vitro systems. He uses artificial lipid bilayers, electrophysiology and DNA origami to measure how forces are sensed and transmitted, and to develop nanoscale tools for regulation of membrane protein function.

For more information please contact Dr Kristal Cain.