G protein-coupled receptors: Nature’s favorite way our cells talk to one another and the outside world | a public lecture Event as iCalendar

(Science Event Tags, Biological Sciences)

28 February 2018


Venue: AMRF auditorium

Location: FMHS, Building 505, 85 Park Road, Grafton

Host: School of Biological Sciences

Cost: Free | Drinks and nibbles follow the lecture

Dr Paul Insel, Hood Fellow and Distinguished Professor of Pharmacology and Medicine at the University of California San Diego
Professor Paul Insel


All organisms, including humans, must respond and adapt to changes in their external and internal environments.

Receptors (equivalent to locks that respond to key-like cues) located on the surface membrane of cells provide a way to solve this need. Such cell surface receptors are present on every type of cell within the body, including in sensory organs such as the eye, nose and mouth. G protein-coupled receptors (GPCRs) are nature’s most widely used type of cell surface receptors that mediate internal sensation, vision, taste and smell.

In this lecture, Hood Fellow Dr Paul Insel, will explain features of GPCRs in terms of the types of signals to which they respond, the physiological and biochemical events that they regulate, their role in human disease and especially as the most frequent targets for approved drugs prescribed for patients. In addition, Dr Insel will highlight recent findings from his laboratory that reveal novel opportunities to target GPCRs for important medical disorders in need of new therapies.

About the speaker

Dr Paul Insel is an award-winning Distinguished Professor of Pharmacology and Medicine at UCSD, with a long-standing interest G-protein-coupled receptors (GPCRs) and their signaling mechanisms.

A current focus involves the identification and targeting of previously unrecognized GPCRs in human cells in health and disease. He has been very actively involved in the training of undergraduates, medical students, graduate students and postdoctoral fellows.